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Showing posts from October, 2019

Understanding Adrenaline Dosage

Have you ever administered adrenaline for anaphylactic shock? I've never had the unfortunate need to. I'm sure anyone who ever does will forever remember the correct dosage. But for me, it is always a confusion. Every time I vaccinate someone at my clinic, I look up the dose of adrenaline just to be sure.

The first problem is the dilutions. Dosages of adrenaline are (or were) mentioned in dilution. 1:1000 & 1:10000. There begins the confusion.

Firstly, let us understand where the 1000 comes from in 1:1000. Have you seen a small vial of adrenaline? That is 1mL. It has effectively 1mg of epinephrine/adrenaline. But why is it called 1:1000? Because 1mL of water = 1g of water = 1000mg. So, the 1:1000 actually refers to 1mg of adrenaline : 1000 mg of water. Unnecessarily complex!

All you had to say was 1mg in 1mL. And that is why this labeling is now being followed in some countries.

So, there you have a small vial - a 1mL vial - with 1mg of adrenaline in it.

Now, let us look a…